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Center of Infection Biology and Immunity

Susanne Krug

TRR 241

Institute of Clinical Physiology

Charité - Universitätsmedizin Berlin


Research interests:

  • Tricellulin: Function, regulation, structure, and clinical impact
  • DFG-TRR 241, B6: Interplay of the impaired tight junction and the subjacent immune cells in IBD

  • DFG-GRK 2318, C2: Role of the tricellular tight junction in inflammatory bowel diseases (IBD)

  • Inflammatory bowel diseases (IBD): Barrier defect via IL-13 and tricellulin

  • Tricellular tight junction as a pathway for macromolecules

  • Drug absorption enhancement by targeting the tricellular TJ

  • DFG KR 3807/7-1: Neuropathic pain resolution by nerve barrier sealing and netrin-1

  • Claudin-17, a paracellular channel for anions

  • Freeze fracture electron microscopy of molcecularly altered tight junctions

  • Two-path impedance spectroscopy for measuring paracellular resistance